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Alcohol use can cause blood glucose to fall too quickly in people with diabetes and may result in hypoglycemia (low blood glucose). Given that metformin lowers blood glucose, the combination of alcohol and metformin could increase the potential for low blood glucose events. The combination of metformin with alcohol may also increase the potential for lactic acidosis, a buildup of lactic acid in the body that develops when cells burn glucose for energy without enough oxygen. This rare but extremely serious complication is more likely to occur in people who binge drink and also take metformin.