To use MK-677 is very simple and easy, because it’s an oral supplement and there aren’t any complicated protocols involved. It can be taken for for an extended period of time, up to 10 weeks. A moderate daily dose is 25 mg. Some experienced lifters use doses of 50 mg and higher. This is however, not necessary if you’re using the supplement for the first time. Adjusting the dose during the cycle is also allowed. If you feel that the dose you’re currently taking is not strong enough to produce the results you expect, you can increase it a bit and see whether it has a stronger effect. And vice-versa, perhaps you can get the same results by taking a lower dosage. Everyone is different, but the standard dose of 25 mg daily does a good job with most users.