Spent couple of months bed ridden due to instant weakness of my leg. I could only pull my leg forward by inching my toes forward. Finally I went to a low cost/free hospital/clinic to get help because I had no insurance. It took months to receive the help I needed and by then, I was already starting to feel better.
Physical therapy got me to walking again but remember feeling a weird feeling in my knee but ignored it. I remember mild inflammation in foot and ankle but it was so mild and would come and go that I figured it was irritation from my leg and not having walked on it for months and months. The pain in my hip had nearly gone away but not quite.
The biosynthesis of eugenol begins with the amino acid tyrosine . L -tyrosine is converted to p -coumaric acid by the enzyme tyrosine ammonia lyase (TAL).  From here, p -coumaric acid is converted to caffeic acid by p -coumarate 3-hydroxylase using oxygen and NADPH . S -Adenosyl methionine (SAM) is then used to methylate caffeic acid, forming ferulic acid , which is in turn converted to feruloyl- CoA by the enzyme 4-hydroxycinnamoyl-CoA ligase (4CL).  Next, feruloyl-CoA is reduced to coniferaldehyde by cinnamoyl-CoA reductase (CCR). Coniferaldeyhyde is then further reduced to coniferyl alcohol by cinnamyl-alcohol dehydrogenase (CAD) or sinapyl-alcohol dehydrogenase (SAD). Coniferyl alcohol is then converted to an ester in the presence of the substrate CH 3 COSCoA, forming coniferyl acetate. Finally, coniferyl acetate is converted to eugenol via the enzyme eugenol synthase 1 and the use of NADPH.