Glyburide, a second-generation sulfonylurea antidiabetic agent, lowers blood glucose acutely by stimulating the release of insulin from the pancreas, an effect dependent upon functioning beta cells in the pancreatic islets. With chronic administration in Type II diabetic patients, the blood glucose lowering effect persists despite a gradual decline in the insulin secretory response to the drug. Extrapancreatic effects may be involved in the mechanism of action of oral sulfonyl-urea hypoglycemic drugs. The combination of glibenclamide and metformin may have a synergistic effect, since both agents act to improve glucose tolerance by different but complementary mechanisms. In addition to its blood glucose lowering actions, glyburide produces a mild diuresis by enhancement of renal free water clearance. Glyburide is twice as potent as the related second-generation agent glipizide.
It is a kind of anabolic steroid drugs, with the promotion of protein synthesis,inhibition of protein gluconeogenesis, lowering blood cholesterol and triglycerides, promoting calcium deposition and reducing the role of bone marrow suppression, etc.. It can make physical enhancement, appetite increasing, weght gaining. This product has a strong effect on anabolic.
Stanozolol Micronized(Winstrol) is widely use to prevent and treat hereditary angioedema,severe trauma,chronic infection,malnutrition and other consuming diseases, and also for the treatment of chronic consuming disease and weight losing after surgery, old and feeble, stunted children,osteoporosis, aplastic anemia. It is also used to prevent long-term usage of adrenal insufficiency caused by corticosteroids.