Propionate de calcium

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Certificate of Analysis for Magnesium Chloride Anhydrous Magnesium Chloride Anhydrous MOLECULAR FORMULA MgCl2
MOLECULAR WEIGHT
Particulars .............. Specification .................... Results
Assay as MgCl2 ........... Min 98% .......................... %
Identification ........... Positive for Chloride & Magnesium- Positive for Chloride & Magnesium
Solubility ............... Freely soluble in water .......... Freely soluble in water
Description .............. A white deliquescent powder ...... A white deliquescent powder
.......................... free from visible impurities...... free from visible impurities
pH of 10% w/v solution ... - ..........................
Sodium as Na ............. 50 ppm max ....................... 10 ppm
Lead as Pb ............... 4 ppm max ........................ 1 ppm
Moisture ................. 2% max ........................... %
Heavy metals ............. 20 ppm max ....................... 4 ppm
Matter insoluble in water 1000 ppm max ..................... 560 ppm
Sulfate as SO4 ........... 300 ppm max ...................... 15 ppm
Arsenic .................. 1 ppm max ........................ Nil
Iron as Fe ............... 20 ppm max ....................... 5 ppm
Total Aerobic Count ...... 1000 cfu/g max ................... 410 cfu/g

Fluid and electrolyte disturbances: Retention of sodium, chloride, water, potassium, calcium, and inorganic phosphates.
 
Gastrointestinal: Nausea, cholestatic jaundice, alterations in liver function tests, rarely hepatocellular neoplasms and peliosis hepatis (see WARNINGS ).
 
Hematologic: Suppression of clotting factors II, V, VII, and X, bleeding in patients on concomitant anticoagulant therapy, and polycythemia.
 
Nervous system: Increased or decreased libido, headache, anxiety, depression, and generalized paresthesia.
 
Allergic: Hypersensitivity, including skin manifestations and anaphylactoid reactions.
 
Vascular Disorders: venous thromboembolism

Miscellaneous: Inflammation and pain at the site of intramuscular injection.

Metabolism of propanoate begins with its conversion to propionyl coenzyme A (propionyl-CoA), the usual first step in the metabolism of carboxylic acids. Since propanoic acid has three carbons, propionyl-CoA can directly enter neither beta oxidation nor the citric acid cycles. In most vertebrates, propionyl-CoA is carboxylated to D-methylmalonyl-CoA, which is isomerised to L-methylmalonyl-CoA. A vitamin B 12 -dependent enzyme catalyzes rearrangement of L-methylmalonyl-CoA to succinyl-CoA, which is an intermediate of the citric acid cycle and can be readily incorporated there.

Propionate de calcium

propionate de calcium

Metabolism of propanoate begins with its conversion to propionyl coenzyme A (propionyl-CoA), the usual first step in the metabolism of carboxylic acids. Since propanoic acid has three carbons, propionyl-CoA can directly enter neither beta oxidation nor the citric acid cycles. In most vertebrates, propionyl-CoA is carboxylated to D-methylmalonyl-CoA, which is isomerised to L-methylmalonyl-CoA. A vitamin B 12 -dependent enzyme catalyzes rearrangement of L-methylmalonyl-CoA to succinyl-CoA, which is an intermediate of the citric acid cycle and can be readily incorporated there.

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