The non-human primate models of AIDS, using HIV-2, SHIV, and SIV in macaques, have been used as a complement to ongoing research efforts against the virus. The drug tenofovir has had its efficacy and toxicology evaluated in macaques and found long-term/high-dose treatments had adverse effects not found using short-term/high-dose treatment followed by long-term/low-dose treatment. This finding in macaques was translated into human dosing regimens. Prophylactic treatment with anti-virals has been evaluated in macaques because an introduction of the virus can only be controlled in an animal model. The finding that prophylaxis can be effective at blocking infection has altered the treatment for occupational exposures, such as needle exposures. Such exposures are now followed rapidly with anti-HIV drugs, and this practice has resulted in measurable transient virus infection similar to the NHP model . Similarly, the mother-to-fetus transmission, and its fetal prophylaxis with antivirals such as tenofovir and AZT, has been evaluated in controlled testing in macaques not possible in humans, and this knowledge has guided antiviral treatment in pregnant mothers with HIV. "The comparison and correlation of results obtained in monkey and human studies are leading to a growing validation and recognition of the relevance of the animal model. Although each animal model has its limitations, carefully designed drug studies in nonhuman primates can continue to advance our scientific knowledge and guide future clinical trials."   
Unfortunate though it may be, a single uncouth act committed by a single unprofessional officer can impact the entire law enforcement profession. Rarely does the public make a distinction between uniforms; at the end of the day, all police officers look and act the same in the eyes of the average citizen. That's why it is so vitally important that each and every officer does her utmost best to maintain and build on the trust that the public has given her, instead of squandering it simply for the sake of bravado, greed or self-gratification.
One tool traders use to identify a trend in stock price is the trend line. It is a line drawn between the high and low point for a stock over a period of time. If the stock price goes up from $10 to $20 to $30 over a three year period, the analyst can plot a line from $10 to $30 starting in year one and ending in year three. The first year marks the first plot in the series, it is the baseline price of $10. The second year represents the beginning of the trend at $20, and the third year marks the continuation, or possibly the end of the trend, at $30. In this way, trend lines can be used to either predict the next data point along the trend or look for a reversal of the trend.